Double Wood Supplements idine (10mg of 99% idine 3HCL - Third Party Tested) 120 Capsules - Over 100x More Potent Than Wheat Germ Extract for Cell Membrane, Supports Health Aging

One of my favorite Brand producing supplements.

product arrived on time.

Buen producto, un poco alto de precio

Spermidine levels naturally decline with age — by the time you’re over 50, your levels are significantly lower than in youth. Research suggests that spermidine may support autophagy, the body’s process of clearing out damaged or senescent cells. Some studies also show potential synergy with flavonoids like fisetin, although the science is still developing. I’m choosing this Double Wood brand because they have a strong reputation for quality, transparency, and third-party testing. It also fits well into the longevity routine inspired by Dr. David Sinclair’s work (although he does not endorse any particular brand). For me, this supplement has been a valuable addition to my overall health and anti-aging regimen, and the price point is excellent for the quality.

Me llego todo bien en tiempo y forma, ojala manejen promociones ya que los suplementos se han vuelto un lujo y mas estas sustancias que deben ser muy baratas ya que son del trigo pero ahora con otro nombre valen una fortuna

These guys are gaining a good reputation and so I decided to purchase from them rather than the usual vendor I use because their price was lower and the quality seems just as good. Spermidine is a natural polyamine that animal studies have shown stimulates autophagy, a process that recycles cellular components and may have anti-aging effects. Spermidine levels decline with aging, and some studies suggest that increasing spermidine intake with food or supplements may improve health and longevity. However, there are very few human studies using spermidine 10 milligrams as a supplement. I found only one clinical trial that used this dose in 100 older adults for 90 days to test its effect on memory and cognitive decline. The results were not very impressive, as there was no significant difference between the spermidine group and the placebo group on any of the cognitive tests. Another clinical trial is currently recruiting participants to test the metabolic responses to spermidine supplementation at doses of 5 or 10 milligrams per day for 12 weeks.The aim is to measure changes in biomarkers related to inflammation, oxidative stress, mitochondrial function, autophagy and aging. Therefore, it seems that more research is needed to establish the optimal dose and duration of spermidine supplementation for humans, as well as its safety and efficacy for various health outcomes. But there is a lot of interest from legitimate researchers, because the non-human studies look so promising. It's typical that the early studies on mice don't directly translate, but there wouldn't be a lot of activity researching the potential if there wasn't real evidence that there is real potential! Stay healthy, stay safe, take care.