

💼 Stay itch-free, stay unstoppable — relief that works as hard as you do!
E45 Itch Relief Cream is a clinically formulated, non-greasy treatment combining 5% urea and 3% lauromacrogols to instantly soothe itching and skin irritation caused by eczema, dermatitis, and dry skin conditions. Trusted for over 60 years, it moisturizes deeply while calming flare-ups, making it an essential skincare ally for professionals seeking fast, effective relief without compromise.





| ASIN | B001PMM1LI |
| ASIN | B001PMM1LI |
| Age Range Description | Adult |
| Allergen Information | Contains: Almonds Free |
| Best Sellers Rank | 478 in Health & Personal Care ( See Top 100 in Health & Personal Care ) 1 in Cortisone Treatments |
| Brand | E45 |
| Customer Reviews | 4.6 4.6 out of 5 stars (7,421) |
| Customer reviews | 4.6 4.6 out of 5 stars (7,421) |
| Date First Available | 21 Aug. 2008 |
| Format | Cream |
| Is discontinued by manufacturer | No |
| Item model number | 348712 |
| Language | English |
| Manufacturer | Reckitt Benckiser |
| Manufacturer contact | MA holder: Karo Pharma AB, Stockholm, Sweden. Reckitt Benckiser Healthcare (UK) Ltd, HU8 7DS. RB NL Brands B.V., WTC Schiphol Airport, Schiphol Boulevard 207, 1118 BH Schiphol, Netherlands. |
| Product Dimensions | 15.39 x 5.41 x 5 cm; 120 g |
| Serving Recommendation | Apply a thin layer of the E45 Itch Relief Cream to the affected area(s) of clean, dry skin. Gently massage the cream into the skin until fully absorbed. Use as needed, up to three times daily, or as directed by a healthcare professional. Avoid contact with eyes. If irritation occurs, discontinue use. |
| Units | 100.0 Grams |
| Weight | 100 g |
K**A
E45 Relief Cream
It takes a long time for the cream to run out and it is great for pain relief as it helps to cool the skin and stop the itchiness.
G**0
Great for clear skin!
This stuff is amazing, and gets rid of dermatitis facial rash in days, esp. as has built-in moisturiser. Works as well as anti-bacterial cream I get from Doctor. However, doesn't stop it coming back, so you may have to use it regularly!
L**A
E45 itch relief cream100g
This didn't stop my itching but might do for others the quality is good and the size is good great for your bag or taking on holiday
A**J
E45 Itch Relief Cream
Bought this for elderly father who was itching arms and forehead with dry skin. Always use E45 but this cream is a step up and it stopped him itching almost immediately. Decent price compared to high street pharmacy and reordered another tube as BF prices too good to resist and cream will be used. It’s not too greasy and as long as applied in direction of hair growth on arms, it moisturises the skin well and sinks in not leaving a greasy surface.
L**N
Great
Found it’s the only product that works to stop irritation from eczema
J**E
Only thing that works.
For years I've been prescribed so many different creams, lotions and oh-so- helpful advise like "keep your skin dry" . Nothing worked, except this cream Honestly it's amazing. Stops the insane itching within minutes, and makes the skin much less sore.
K**M
Good product
This cream actually works for me..non greasy and fast acting.
B**D
Didn't work for me, but it may not be the product at fault
Sadly this product didn't work for me and I'm still as itchy as I have been for the past few days. This, however, could be the result of a problem it simply can't fix. It's just a relief cream after all. I wasn't expecting it to clear up my itching permanently, but I was hoping it would at least tone it down a little so I could at least get some sleep, which it didn't in the slightest. I'd still recommend to give it a go if your itching isn't too serious. It's rather affordable and doesn't leave my hands all greasy. Seems to absorb just fine, too (though I understand others have complained it does not). I hope you have better luck than I did *scratch scratch*
L**E
Good Day, ehm! that is how I start my beloved review about this cream. in the month of October I was in Ireland and had a sudden rash on my face, I had to go and see a doctor, which she has recomende E45 to use take back to Canada, at the same time; she has said, I can order it from Amazon. now I look at my face, so clean. what can I say to you Amazon. you are my go to when I need something, I mean anything! you guys rock!!!!!!!!!!!!!!!!!!!!!!!!! Have a pleasant day! Sunny from Oakville, Ontario (Canada)
L**H
Works well on itch/burn from eczema and moisturises as well. Very happy with this cream on 2nd tube and will order more. Very fast delivery. Arrived 4 days earlier in Australia than quoted. Great that it has free delivery too.
R**H
Can’t buy in Australia so got it on amazon item does the trick and slowly relives the itch not instant but way cheaper than a script item.
G**Y
Good product....
A**R
Very effective and also appreciate the punctual and timely delivery.Will be handy during winter months when skin is dry.
Trustpilot
5 days ago
2 months ago