

🌟 Wake up to younger, glowing skin — your nightly glow-up essential!
ISDIN Isdinceutics Retinal Advanced is a scientifically formulated night serum combining retinaldehyde and melatonin in a dual-phase system to visibly reduce wrinkles by 43% within 4 weeks. Designed for all skin types, including sensitive skin, it smooths texture, boosts radiance, and enhances skin firmness while maintaining ingredient stability for maximum effectiveness.
















| ASIN | B0CC9W3VWR |
| Age Range (Description) | Adult |
| Age Range Description | Adult |
| Best Sellers Rank | #53,552 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #1,095 in Facial Serums |
| Brand | ISDIN |
| Brand Name | ISDIN |
| Customer Reviews | 4.5 out of 5 stars 185 Reviews |
| Item Form | Cream |
| Item Volume | 1.7 Fluid Ounces |
| Manufacturer | ISDIN |
| Number of Items | 1 |
| Product Benefits | Retinal Advanced is a night serum that helps visibly reduce wrinkles and fine lines. Formulated with youth-boosting ingredients such as retinaldehyde, it helps smooth and rejuvenate the skin. |
| Recommended Uses For Product | Wrinkles |
| Skin Type | All |
| Special Ingredients | vitamin_e |
| Specific Uses For Product | Apply at night onto clean, dry skin. Press pump twice to dispense the right amount into hand, mix well, and apply. Always apply a broad spectrum sunscreen the next morning and throughout the day. |
| Target Use Body Part | Skin |
| Unit Count | 1.7 Fluid Ounces |
M**E
I love it
Value for money, effectiveness, excellent texture.
R**B
First Retinoid Product - so far so good!
I’ve never used retinal/retinol etc, so using this product is my very first attempt. I am 40+, fair skin, sensitive skin, dry skin, med/large pores, still prone to hormonal breakouts, some sun damage freckling, pretty deep 11s, and very minor wrinkles anywhere else. I started using this right around 2/1/24. It’s now 2 months of almost nightly use since (I’ve skipped a couple nights here or there just from schedule issues). I do use a full 2 pumps each time, every night, and I run the excess down my neck and upper chest to help with signs of aging there. I thought FOR SURE I would have bad peeling, redness, etc because I have sensitive skin and usually EVERYTHING makes me red or break out. But this hansy been bad at all! I started to think that might mean it’s a dud product, but I have been going thru “purge” for about 3-4 weeks. Not constant, but a couple of rounds of very agitated pimples. Moreso than I usually get, and I am used to have them every month with my cycle. So that makes me feel like it’s doing SOMETHING! I think I may be on the downward slope of the purge…. Hopefully. How does my skin feel or look? Well, it actually does feel more hydrated and softer than ever. I love that! It looks slightly more even tone (between the breakout areas when I’m having pimples and generally all over when I’m not having a breakout.) I also feel like I’m seeing a little more radiance or glow. Nothing miraculous, but just a little more shine and luster. I have not noticed a reduction in my deep 11s or my 2 very fine forehead lines. So far I’m happy. It’s such an expensive product I hate that you have to spend so much to find out if it works, but I feel like the signs I’m seeing now support continued use and expense. At 2 months, it looks to me like I might have 1 month of product left in the jar. For the price I paid, if it lasts 3 months, that’s about $62 a month ($744 a year!). I’ve never had an rx from a derm, so I’m not sure how that compares to prescription and office visit costs. I’m going to continue trying this for the full year. If I feel confident that I’m seeing results, I’ll do a cost comparison of actually getting on and maintaining a retinoid rx or just continuing this product. Will update!
K**T
Excellent retinol
Looooooove what this ISDIN retinol does to my skin. I purchased it originally from a pharmacy overseas as a recommendation from the pharmacist. I wanted to have smoother skin. I purchased it again off Amazon when I ran out. Great product! Just a pea size amount at night and moisturizer afterwards.
A**R
Top skincare product
The best product!! Have been using for 9 months and have seen a significant improvement. My skin is more glowing and have seen a decrease in dark spots. Worth the price
Y**A
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Me encanta este producto
J**Z
Great Results with a Gentle Retinal Formula
I've been using ISDIN's Retinal Advanced serum for a few weeks now, and I'm genuinely impressed with how it's working for my skin. The formula feels luxurious and absorbs quickly without leaving any greasy residue. I have sensitive skin, and I was worried about irritation (since this contains retinaldehyde), but it's been surprisingly gentle—no peeling, redness, or dryness. I’ve noticed a more even tone and a slight softening of fine lines, especially around my eyes and mouth. The added melatonin is a nice touch—I don’t know if it’s doing anything directly, but it makes me feel like I’m supporting my skin’s nighttime repair. My only reason for giving 4 instead of 5 stars is the price. While the product works well, it is a bit expensive compared to others with similar ingredients. Still, the quality and effectiveness make it worth considering if you're looking for a high-end night serum that delivers results without being harsh.
L**.
Líneas de expresión
La piel mejora desde el primer día . Me mejoró las líneas de expresión y la apariencia de la piel .
R**L
El mejor producto que he comprado para
La mejor inversión que he hecho en mi skincare, mi piel cambió mucho desde las primeras aplicaciones, lo amo no me arrepiento de haberlo comprado, por supuesto que voy a comprar otro cuando se me termine
Trustpilot
1 week ago
2 months ago