

✨ Unlock your skin’s youthful power with every drop 💧
HydroPeptide Power Serum is a peptide-rich, anti-aging treatment designed to visibly reduce fine lines and wrinkles while deeply hydrating and firming mature skin. Developed by geneticists and powered by patented peptide technology, it combines collagen-supporting antioxidants and hyaluronic acid in a lightweight, non-irritating formula that layers effortlessly under skincare and makeup. Ideal for dry, post-menopausal skin, this serum enhances skin texture, tone, and resilience with clinically clean, cruelty-free ingredients.


















| ASIN | B000URKRXS |
| Best Sellers Rank | #109,513 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #2,161 in Facial Serums |
| Customer Reviews | 4.4 4.4 out of 5 stars (113) |
| Is Discontinued By Manufacturer | Yes |
| Item model number | RPS |
| Manufacturer | HydroPeptide |
| Product Dimensions | 1.18 x 1.18 x 4.72 inches; 1.8 ounces |
| UPC | 853666001085 885127381085 |
T**G
Excellent Anti-Wrinkle Peptide Serum for Dry, Aging Skin (52, Post-Menopausal)
I’m 52 with post-menopausal, dry, mature skin, so I’m extremely picky about “lifting” and “anti-wrinkle” serums—most either feel sticky, irritate my skin, or give a short-lived tightening effect that disappears the minute you put moisturizer over it. This HydroPeptide Power Serum has been a genuinely impressive exception for me, and it’s the kind of product that makes your routine feel more effective without making your skin feel overworked. First, the texture and application are excellent. It has that silky, cushiony serum feel that spreads easily and absorbs quickly, so you don’t need a lot. It sits beautifully on the skin—no greasy residue, no heavy film—and it layers well under richer moisturizers (which I absolutely need). With mature dry skin, that layering matters more than people realize: if a serum pills or stays tacky, you end up skipping it, and nothing “anti-aging” works if you don’t consistently use it. This one is easy to reach for and easy to keep in the routine. What I noticed most is how “plumped” my skin looks and feels after using it consistently. I’m not talking about an unnatural tight or shiny look—more like that smoother, healthier skin quality that makes fine lines look softened because your skin is better hydrated and supported. My face feels a bit more resilient and bouncy, especially in areas where post-menopausal dryness makes texture show up more (around the mouth, lower cheeks, and forehead). It gives a firmer look over time, but in a subtle, believable way. I also appreciate that this serum feels like it’s doing multiple jobs. The label mentions wrinkle-relaxing peptides, a vitamin C activator, and skin matrix support, and that’s honestly how it performs—like a “power step” that supports radiance and firmness while also helping the skin feel more comfortable and less depleted. I’m cautious with vitamin C products because many classic formulas sting or leave me dry, but this is not that kind of experience. I didn’t get the burning or sensitivity that I associate with stronger vitamin C serums, and I didn’t notice any increase in dryness. For my skin type, that’s a huge win. Another reason I’m giving this five stars is that it works in real life, not just in theory. I can use it in the morning and still layer sunscreen and makeup without issues. I can use it at night and still apply a barrier-supporting cream over it without pilling. And because the bottle is an airless pump, it feels more hygienic and stable than a dropper bottle you’re opening constantly. I like packaging that protects the formula and dispenses the right amount—especially when you’re paying for a “treatment” serum and not just a basic hydrator. I also want to mention tolerance, because that’s make-or-break for mature skin. My skin can get reactive if I push too many actives at once, and this serum has been very comfortable to use. No redness, no stinging, no tightness. If you’re someone who wants anti-aging benefits but also needs to protect the skin barrier (especially if your skin is dry, mature, or post-menopausal), this feels like a smart choice because it supports firmness and lines without that harsh, stripped feeling. In terms of results, I think this is a great “skin quality” product. It won’t replace in-office procedures or a prescription retinoid, but it absolutely supports the look of smoother texture and more hydrated, firmer skin—exactly what I want from a peptide-forward serum. If your lines look worse when your skin is dehydrated (which is very common after menopause), this helps in a way that’s noticeable and consistent. Overall, HydroPeptide Power Serum has earned a permanent spot in my routine. It’s elegant, layers well, feels gentle, and gives that plumped, healthier look that makes mature skin look more refreshed. If you’re looking for a well-rounded anti-wrinkle serum that focuses on peptides, firmness, and barrier-friendly radiance—and you have dry or mature skin—this is absolutely worth trying.
J**L
Worth the cost!
Living in Utah my skin is very dry. This serum has worked wonders on hydrating my skin. It’s expensive but I keep coming back for more so it must be worth it. I use one pump a day before bed and feel like that is a sufficient amount. There’s no real scent to it and doesn’t feel sticky. My skin is soft and looks young.
C**N
Facial luxury
I really love this product. It’s light and moisturizing to my skin.
M**N
Thrilled !
I've been using HydroPeptide for 5 years at least. I am thrilled with my results. I am 68 years old and and, according to general consensus, I appear to be in my early 50's!! All the products are excellent.
M**L
Nice serum
This serum is great. It evens out skin tone, soaks in nicely before moisturizer, doesn’t smell weird or strongly and seems to last. Which is good, because it’s expensive. The bottle keeps it air tight and one pump is enough to cover the face and under chin area.
J**S
Mediocre results at best
Results were fleeting. My skin seems tighter but I don’t like the smell and it’s rather slimy on my skin. Overall, I like many of the products that they make but this one isn’t for me.
D**R
Great stuff
I love it…..I can feel it softening my skin when I have it on.
D**B
Something Changed with this Product - Returned it!
Though expensive, I have purchased this products several times in the past. The content of the last bottle I purchased was not the same as previous purchases. It had a strange odor and it didn’t feel like the same product. Very disappointing. I’d like to order it again to see if it was just a bad batch but, I’m leery.
A**R
Awesome serum. 👍👍
M**S
I’m just worried about the smell or is that normal?
Trustpilot
3 weeks ago
4 days ago