---
product_id: 66321844
title: "Advanced Serum Refill"
brand: "regenerate"
price: "$90"
currency: NZD
in_stock: false
reviews_count: 13
url: https://www.desertcart.nz/products/66321844-advanced-serum-refill
store_origin: NZ
region: New Zealand
---

# 3 minutes per day, 3 consecutive days monthly 82% enamel mineral regenerated in 3 days NR-5™ patented enamel mineral technology Advanced Serum Refill

**Brand:** regenerate
**Price:** $90
**Availability:** ❌ Out of Stock

## Summary

> 🦷 Elevate your smile game—because your enamel deserves a comeback!

## Quick Answers

- **What is this?** Advanced Serum Refill by regenerate
- **How much does it cost?** $90 with free shipping
- **Is it available?** Currently out of stock
- **Where can I buy it?** [www.desertcart.nz](https://www.desertcart.nz/products/66321844-advanced-serum-refill)

## Best For

- regenerate enthusiasts

## Why This Product

- Trusted regenerate brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Time-Efficient Treatment:** Only 3 minutes a day for 3 days monthly—fits perfectly into your busy schedule.
- • **Powerful NR-5™ Technology:** Exclusive patented formula delivers fresh enamel minerals that integrate seamlessly.
- • **Boosts Toothpaste Performance:** Enhances REGENERATE Advanced Toothpaste effectiveness by 43% for maximum results.
- • **Supports Sensitive & Aging Teeth:** Targets 80% of common enamel-related issues like sensitivity, yellowing, and transparency.
- • **Clinically Proven Enamel Regeneration:** Reverses early enamel erosion with 82% mineral restoration in just 3 days.

## Overview

REGENERATE Advanced Serum Refill harnesses patented NR-5™ technology to clinically regenerate 82% of tooth enamel mineral in just 3 days. Designed for busy professionals, it requires only 3 minutes of use per day over 3 consecutive days monthly. This serum not only reverses early enamel erosion but also boosts the effectiveness of REGENERATE Advanced Toothpaste by 43%, tackling common enamel problems like sensitivity, yellowing, and transparency. Ideal for those seeking a scientifically backed, time-smart solution to maintain strong, healthy teeth and a confident smile.

## Description

Product Description REGENERATE Enamel Science™ is the first oral care regime with NR-5™ technology able to regenerate tooth enamel* with exactly the same mineral it is made of, reversing the early enamel erosion process. Clinically proven. 80% of common tooth problems, such as sensitivity, transparency and yellowing, are caused by enamel erosion. Enamel is the hardest substance in the body protecting the teeth core underneath. Enamel gets eroded day after day, it happens to everyone, at all ages. The main causes of enamel damage include consuming acidic food and drinks such as fruit, fruit juices and soda, and undergoing teeth bleaching and aligner treatments. Once enamel is eroded, it is not possible for the body to restore it. After 9 years of research, the impossible is made possible with REGENERATE™ Enamel Science, powered by the exclusive and patented NR-5™ technology. At each use, active NR-5™ ingredients combine to form a fresh supply of enamel minerals. These wrap and integrate onto teeth helping to regenerate enamel mineral * with exactly the same mineral tooth enamel is made of. Each REGENERATE Enamel Science™ Advanced Enamel Serum kit contains one NR-5™ Advanced Enamel Serum and one Activator Gel – does not contain mouth trays or mixing stick. When combined with the Activator Gel, the NR-5™ Serum unleashes a concentrated boost of the formula, helping to reverse the early enamel erosion process. The REGENERATE™ Advanced Enamel Serum Kit should be used on a monthly basis for 3 consecutive days. It is preferable to apply at night time and not to consume food or drink immediately after use. Suitable to use when undergoing aligner treatments. After only 3 days, REGENERATE™ Advanced Enamel Serum boosts the effectiveness of REGENERATE™ Enamel Science Advanced Toothpaste by 43%** to maximise the power of enamel mineral regeneration and helps you to keep your teeth strong and healthy. 82% of enamel mineral regenerated in 3 days**, clinically proven. *Acts on early invisible stages of enamel erosion. Helps to regenerate enamel by restoring its mineral content and micro hardness with regular use. Clinically proven. **As demonstrated in a 3-day in vitro test measuring enamel microhardness: combined use of Advanced Toothpaste and Boosting Serum vs Advanced Toothpaste only. *** As demonstrated in a 3 day in vitro test measuring enamel micro hardness: Combined use of toothpaste and serum. Ingredients NR-5 Serum: Glycerin, Calcium Silicate, PEG-8, Trisodium Phosphate, Sodium Phosphate, Aqua, PEG-60, Sodium Lauryl Sulfate, Sodium Monofluorophosphate, Aroma, Hydrated Silica, Synthetic Fluorphlogopite, Sodium Saccharin, Polyacrylic Acid, Tin Oxide, Limonene, CI 77891.Activator Gel: Aqua, Glycerin, Cellulose Gum, Sodium Fluoride, Benzyl Alcohol, Ethylhexylglycerin, Phenoxyethanol, CI 42090.Activator Gel contains: Sodium Fluoride (1450 ppm F) P.when('A').execute(function(A) { A.on('a:expander:toggle_description:toggle:collapse', function(data) { window.scroll(0, data.expander.$expander[0].offsetTop-100); }); }); Box Contains Each REGENERATE Advanced Enamel Serum refill kit contains one NR-5™ Serum and one Activator Gel. Manufacturer Contact Information Unilever Dept ER Wirral CH63 3JW UK See more

Review: It Works - I bought this on my dentist’s recommendation as I have defective tooth enamel. I am very impressed with its performance. After my first cycle of 3 consecutive nights’ treatment my teeth have lost their translucent look and are now a healthy, more solid white colour (different from the results of tooth whitening). I’m not sure how many treatment cycles are in the pack but I would guess another two. I was a bit annoyed that the full kit with trays is out of stock so I used my tooth whitening trays instead. These aren’t ideal because their nooks and crannies make mixing the serum and activator awkward, so when the kit with trays is back in stock I will buy it. I’m using the toothpaste and mouthwash for maintenance between the monthly treatment cycles. Regenerate is expensive, but so is a lifetime of dental procedures, and if it can help save my teeth it is well worth the money.
Review: Truly effective on me - After a lifetime of porous thin yellowing enamel that could not be bleached as advised by dentists it is best not bleached as overly thin, I tried every product sold on the high street until I decided to look online for newer formulas of bleaching and strengthening products. To my great and very pleasant surprise, I found out my teeth got obviously whitened by a toothpaste with small doses of peroxide used daily over a longer period. Having achieved a positive slow progress on the colour of my teeth (I used to smoke, still drink tea and coffee daily and love blueberries and my teeth were yellow and greyish almost off the charts), despite of good hygiene and regular dental polishes-I decided to look into newer strengthening products. I found this, and noticed immediate thickening and whitening effect after the first use, with a high shine of my front teeth. The second dose felt nice, thick and hard under the tongue, but the colour appeared the same, so my enamel seems to be saturating to its potential. This product is a miracle that worked really well for me, and I intend to purchase again. I did not buy a toothpaste from the same brand but used a similar high street brand in the evenings and strong whitening toothpaste with peroxide in the mornings that I also found here. I hope this helps, and people with thin yellowing thin enamel try it!

## Features

- REGENERATE Enamel Science is the first oral care system able to regenerate tooth enamel mineral*, reversing the early enamel erosion process, keeping teeth healthy and strong
- Its unique NR-5 ingredients combine to form a fresh supply of tooth enamel minerals which wrap and integrate onto teeth
- 80% of common tooth problems such as sensitivity, transparency and yellowing are caused by enamel erosion and acid attacks
- Use for 3 minutes, 3 consecutive days a month. 82% of tooth enamel mineral is regenerated after 3 days***, clinically proven
- Boost the effectiveness of REGENERATE Advanced Toothpaste by 43%**
- For best results, use in combination with REGENERATE Advanced Toothpaste

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B01LA1XSYM |
| ASIN  | B01LA1XSYM |
| Best Sellers Rank | 23,263 in Health & Personal Care ( See Top 100 in Health & Personal Care ) 97 in Dental Care Kits |
| Brand | Regenerate |
| Customer Reviews | 4.3 4.3 out of 5 stars (645) |
| Customer reviews | 4.3 4.3 out of 5 stars (645) |
| Date First Available | 30 Aug. 2016 |
| Format | Gel |
| Is discontinued by manufacturer  | No |
| Item model number  | 9195422 |
| Manufacturer  | Unilever |
| Manufacturer contact | Unilever Dept ER Wirral CH63 3JW UK |
| Product Dimensions  | 3.8 x 9.1 x 12.7 cm; 80 g |
| Units | 1 Count |
| Volume | 32 Millilitres |
| Weight | 0.08 Kilograms |

## Product Details

- **Brand:** Regenerate
- **Item form:** Gel
- **Item volume:** 32 Millilitres
- **Item weight:** 80 Grams
- **Material feature:** Feuchtigkeit
- **Number of items:** 2
- **Product benefits:** Regenerates
- **Scent:** fresh
- **Skin type:** Combination
- **Unit count:** 1 Count

## Images

![Advanced Serum Refill - Image 1](https://m.media-amazon.com/images/I/71g83kVTRBL.jpg)
![Advanced Serum Refill - Image 2](https://m.media-amazon.com/images/I/71KWv2UbqML.jpg)
![Advanced Serum Refill - Image 3](https://m.media-amazon.com/images/I/71Nm54PumVL.jpg)

## Questions & Answers

**Q: Hi does this work helping the worn enamel if anybody has used this and has it worked?**
A: Yes my sister and myself use it

**Q: Can you use this product if you have caps in between your normal teeth.. thanks**
A: I don’t know the answer but it should bevon the leaflet inside the bix

**Q: Does it heal gums**
A: Just teeth. Doesn't do gums any harm though.

**Q: Will this work to cover problem discoloured teeth**
A: I noticed no real difference and have since returned to standard toothpaste

## Customer Reviews

### ⭐⭐⭐⭐⭐ It Works
*by M***N on 26 November 2025*

I bought this on my dentist’s recommendation as I have defective tooth enamel. I am very impressed with its performance. After my first cycle of 3 consecutive nights’ treatment my teeth have lost their translucent look and are now a healthy, more solid white colour (different from the results of tooth whitening). I’m not sure how many treatment cycles are in the pack but I would guess another two. I was a bit annoyed that the full kit with trays is out of stock so I used my tooth whitening trays instead. These aren’t ideal because their nooks and crannies make mixing the serum and activator awkward, so when the kit with trays is back in stock I will buy it. I’m using the toothpaste and mouthwash for maintenance between the monthly treatment cycles. Regenerate is expensive, but so is a lifetime of dental procedures, and if it can help save my teeth it is well worth the money.

### ⭐⭐⭐⭐⭐ Truly effective on me
*by C***R on 8 March 2023*

After a lifetime of porous thin yellowing enamel that could not be bleached as advised by dentists it is best not bleached as overly thin, I tried every product sold on the high street until I decided to look online for newer formulas of bleaching and strengthening products. To my great and very pleasant surprise, I found out my teeth got obviously whitened by a toothpaste with small doses of peroxide used daily over a longer period. Having achieved a positive slow progress on the colour of my teeth (I used to smoke, still drink tea and coffee daily and love blueberries and my teeth were yellow and greyish almost off the charts), despite of good hygiene and regular dental polishes-I decided to look into newer strengthening products. I found this, and noticed immediate thickening and whitening effect after the first use, with a high shine of my front teeth. The second dose felt nice, thick and hard under the tongue, but the colour appeared the same, so my enamel seems to be saturating to its potential. This product is a miracle that worked really well for me, and I intend to purchase again. I did not buy a toothpaste from the same brand but used a similar high street brand in the evenings and strong whitening toothpaste with peroxide in the mornings that I also found here. I hope this helps, and people with thin yellowing thin enamel try it!

### ⭐⭐⭐⭐ Teeth feel stronger
*by S***R on 13 January 2021*

After 3 uses teeth do feel stronger and brighter. Some lines, enamel cracks, and discolouration still apparent but slightly less noticeable than before use. Pictures have been numbered 1 = after 1st use / 3 = after 3rd use. I have my own tray so cannot comment on the tray provided. Mixing formulae a bit tricky - I used the end of a platic tooth floss which did the job well. There's enough product left for next month. Product has not caused any discomfort or post use sensitivity as some witeners do. I'm using in conjunction with the toothpaste. 4 stars as there is still some transparency in the front teeth (I'd say 30/50% improvement rather than 80%) and no improvement to a small area of damaged enamel on the side of a molar.

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---

*Product available on Desertcart New Zealand*
*Store origin: NZ*
*Last updated: 2026-02-21*