








🐾 Elevate your dog’s wellness game—because every pup deserves to feel like a puppy again!
PranaPets Lignans & Melatonin with Biotin Blend is a scientifically adjusted supplement designed for dogs over 25 lbs to naturally alleviate symptoms of Cushing’s disease. Featuring a precise lignans and melatonin formula combined with biotin, it supports healthy cortisol levels, promotes skin and coat health, and excludes artificial additives for a clean, effective daily regimen.















| ASIN | B0DFJCL5BG |
| ASIN | B0DFJCL5BG |
| Age Range Description | All Life Stages |
| Best Sellers Rank | #7,593 in Pet Supplies ( See Top 100 in Pet Supplies ) #42 in Dog Herbal Supplements |
| Brand Name | PranaPets |
| Color | Beige |
| Customer Reviews | 4.3 4.3 out of 5 stars (513) |
| Date First Available | August 22, 2024 |
| Date First Available | August 22, 2024 |
| Directions | Dogs 26-40 Lb: 2-3 Tablets Per Day. Recommend 1 tablet in the morning & 1-2 tablets at bedtime |
| Included Components | Tablets |
| Item Package Dimensions L x W x H | 3.78 x 1.93 x 1.89 inches |
| Item Weight | 0.09 Kilograms |
| Item model number | PPMELLIG2-BIO |
| Item model number | PPMELLIG2-BIO |
| Manufacturer | PranaPets |
| Manufacturer | PranaPets |
| Model Name | L&M w/ Biotin |
| Package Dimensions | 3.78 x 1.93 x 1.89 inches; 3.21 ounces |
| Size | Over 25 lb (w/ Biotin) |
| Specific Uses for Product | Active |
| Target Audience Keyword | dogs |
| Warranty Description | 366 |
D**L
It worked for us and our 13 year old dog.
As far as I’m concerned this stuff really works if your dog has Cushing disease. Our dog started the adrenal gland balance drops and then we included the lignans and melatonin support. She did an about face and is back to her normal self. In fact she’s acting like a puppy again at 13 years old. For all the naysayers out there, maybe it doesn’t work for your dog and I’m sorry but for new people who are considering it, what’s it hurt to try, especially if your dog is getting old and you’re at your wits end. That’s where we were and we tried it and it works great. Good luck to you if you’re going to give it a try. I really hope it works for you and your dog!
L**A
Works great!
This is great for my dog. He sleeps through the night without wandering through the house. He isn’t peeing in my house anymore. I never actually tested him for cushings but he had all the symptoms and this is a much more affordable way to help him. He seems happier and has more energy during the day.
S**S
Keeping my HOPES 🥰🙏🏼🤞🏼up! 🐶
MY personal experience thus far: 🙏🏼 Just started … I have a rescue 🐶 doggy, positivity confident that suffers from Cushing disease / syndrome with major! skin issues / infections, joint pain inflammation and unhappiness and over discomfort about every 3-4 months relapses, sometimes loosing some of his beautiful hair coat🐶, triggered by allergies. The PranaPets Lignans and Metlaronin Blend with Biotin,’ has been recommended by our veterinarian as an alternative holistic treatment according to her advice for us. We Cannot afford to spend the $4,000-$5,000 on 'Cushing’ related -tests related, which STILL could NOT be a 💯 % reliable diagnosis for my dog according to our vet. ☝🏼In the Meantime —our Vet recommended a HEALTHY nutrious restricted food diet, rich in omega oils 3, 5, 7, 9 and special dermatological shampoos conditioner etc (which I found on on Amazon much cheaper). The PRANAPETS is part of our regimen. Our Vet specifically recommended this holistic The blend of ingredients in PRANA🐶PETS, Lignans and Melatonin blend with Biotin that I noticed are FREE of any harmful inactive ingredients according to my purchase. I was buying the INDIVIDUAL ingredient of each in this product, which is MUCH more expensive and not knowing if each dose à was exact or consistent. THIS PRODUCT is Great 👍 !! It is ALL in one!! AND, the BLEND of Active Ingredients is EXACTLY what the Vet recommends or prescribes for ‘something-liké potentially Cushings disease 🦠 and the health & benefits of MY dogs symptoms including his endocrine systems, adrenals and cortisol and thyroid hormones and brain…. we are trying an alternative healthcare approach for now. Amazon has some very good options for probiotics and immune-calm that are helping to provide overall daily maintenance balance AND as I am discovering at a lower cost. ‼️PLEASE 🐶NOTE: I did N🚫t get paid, endorsed, etc or was asked for this review. Thank you . Best !
A**A
BUY IT!
This product is the number 1, favorite thing in my doggy cabinet. My dog was diagnosed with cushings disease over two years ago and I decided to go the holistic route instead of putting him on hard medications. Due to my dogs age, he was getting anxiety at night that lead to him whining for hours, not settling down and not sleeping through the night. This product (I give it to him around 6pm) keeps my dog calm and relaxed! He went for his senior bloodwork last month and his levels look better than two years ago and his cushings is being mostly managed. I just added their liquid adrenal support to his daily diet as well. It works, he’s happier and not on harsh medications which makes both of us happy!
C**L
I saw improvement in two days.
This product has really helped my dog who has cushings. He started sleeping more, but is moving around more when awake. His excessive drinking water improved. And I could even tell that his belly was no longer enlarged. I also bought the adrenal balance . But just today I added the immunity defense. I am hoping it will clear up his dry skin.
D**N
Why bother asking if the dog is over or under 25 pounds it's the same.
Well, I'm very confused. I've been using the product for dogs over 25 pounds now for over 2 years with great results. I re-ordered the other day and first I was sent the one for under 25 pounds. On my old bottle for over 25 pounds the instructions said 1 pill for his size (26 lbs. up to 100 lbs. 1 pill, he is 70 pounds and takes 1 pill)). When I looked at the bottle for under 25 pounds that had come I would have to give him 2 pills. I called Amazon customer service and was told not to return the bottle they would credit me back and send me one for over 25 pounds which they did very promptly but the new bottle for over 25 pounds now says instead of giving him 1 pill like normal he needs to now have 2! First off I'm concerned now that the pills ingredients might not be what they should be and they have added biotin to it too. Secondly, this NOW means instead of having a 90 day supply like I've always had because he now gets 2 pills the supply will only last 45 days!!! I'm really not happy and don't understand this! I'm having trouble uploading a picture of the bottles or else I would post a picture. Has anyone else noticed this? I am very concerned and disappointed.
D**T
I 100% believe this supplement saved my Boston Terrier
We were flirting with a Cushing diagnosis about six months ago, but were unable to confirm with certainty. A friend asked Dr. Google and sent me a link to this product. If you’re familiar with adrenal Cushings and traditional diagnosis and treatment, it’s time consuming and EXPENSIVE. I think had we gone with Vetoryl, she’d still be going in for semi-regular labs (all day, fasting, couple hundred bucks a pop) to get dosage right. I didn’t feel I had much to lose, started her on one pill daily, and noticed a difference in less than a week. Proof came with her checkup this fall, in less than 6 months her ALP went from 1622 in April to 470! Our vet was amazed. One note: at first, she would not eat it solo and it’s too big to hide in food. I bought a cheap pill crusher and used that for a while. Now, I just toss a pill into her bowl of kibble and she eats it fine.
D**Y
Very good for my pets. Keeps them calm at night.
Trustpilot
5 days ago
2 months ago