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🐾 Calm skin, happy pets — because they deserve the best!
Douxo S3 Calm Shampoo features 0.75% Ophytrium, a vet-recommended hypoallergenic formula that soothes itchy, irritated skin in dogs and cats. Clinically proven to reduce itching within 7 days, it also detangles and moisturizes fur, leaving coats soft and shiny. Free from parabens and sulfates, it’s safe for long-term use and supports skin barrier repair for lasting relief.





















| ASIN | B09478KSWG |
| Allergen Information | Hypoallergenic |
| Best Sellers Rank | #1,094 in Pet Supplies ( See Top 100 in Pet Supplies ) #12 in Dog Shampoos |
| Brand | Douxo |
| Brand Name | Douxo |
| Customer Reviews | 4.6 out of 5 stars 3,756 Reviews |
| Included Components | Shampoo |
| Item Form | Mousse |
| Item Type Name | Shampoos & Conditioners |
| Item Weight | 16.9 Ounces |
| Liquid Volume | 16.9 Fluid Ounces |
| Manufacturer | Douxo S3 |
| Manufacturer Part Number | D98120F |
| Material Type Free | Paraben Free, Sulfate Free |
| Model Number | D98120F |
| Product Benefits | Anti-Itch |
| Recommended Uses For Product | Irritated Skin |
| Scent | Fresh, Sweet |
| Scent Name | Fresh, Sweet |
| Special Ingredients | OPHYTRIUM |
| Target Species | dog, cat |
| UPC | 850002593396 |
| Unit Count | 1 Count |
N**E
Wonderful dog shampoo that soothes irritated skin
This shampoo is awesome! It heals hot spots and has made my dogs fur grow back and her fur is soft! Smells great too!
M**A
Excellent relief for itchy, sensitive skin
I bought this shampoo for my dog who suffers from allergies, itching, and irritated skin, especially around the ears. After just a few washes, I noticed a big improvement. The redness and itching were reduced, and my dog seemed much more comfortable. The shampoo is very gentle, has a light scent, and lathers well. It doesn’t dry out the skin and leaves the coat soft and clean. I also like that it’s recommended by veterinarians and contains Ophytrium, which really seems to help calm the skin. If your dog has sensitive skin, allergies, or frequent itching, this shampoo is definitely worth it. I will continue using it and highly recommend it.
A**N
A Lifesaver for My Dog’s Skin — Worth Every Penny
I’ve tried a lot of products to manage my dog’s skin issues, but Douxo S3 Calm is the only shampoo that’s consistently helped. My golden retriever, Luna, has a dust mite allergy and a history of sensitive skin and occasional staph infections, especially when staying in dusty or older environments. This shampoo has become part of our routine, and it’s made a real difference. It’s gentle, fragrance-free, and doesn’t dry her out — even with more frequent use. Her skin looks calmer, less red, and she scratches way less after a bath. I’ve noticed fewer flare-ups since switching to this and sticking to a consistent bathing schedule. If your dog has allergy-prone or reactive skin like mine, this is the one to try. It’s pricey, but it actually works — and that’s what matters.
L**N
Works! Environmental alergies scratching and chewing stopped. It's been 3 days.
My pups have environmental allergies. We used it one time and it's been 3 days no itching. We use the foam on their paws. This is the best. Lathering, softness of fur and effective the first use.
P**U
A great shampoo product for dogs and cats who have itchy. Irritated skin. Worth the money
DouxoS3, calm dogs or cats shampoo with OPHYTRIUM 0.75 for itchy, irritated skin. This shampoo has worked for my three little dogs. It is labeled "A SAFE SKINCARE SOLUTION" Soap, Sulfate and parables free. It has an easy pump top for dispensing, no medicated odor to this shampoo. Great lather, feels very soothing. Safe for small and large dogs and cats. It's nice to see them not feeling itchy or irritated. No more skin scratching. This is a good product in my opinion with no harsh unsafe chemicals. Your dog or cat will thank you for it!!
A**G
Amazing!
This is the only shampoo that has relieved my dog’s itching and healed her skin. It also has improved her fur and allowed it to grown back in the spots it had fallen out. I shampoo her with this every couple weeks and will continue to do so!
1**L
Less itchy
Used with the calm mousse for my lab mix. He has some seasonal allergies or got bit by something and had the itchies so bad that he was creating hot spots. Well the vet recommended the mousse and shampoo and it really has seemed to give him some relief as I have been using the shampoo weekly. It is hard to wait the ten minutes but I have been able to wait a few minutes before rinsing. His coat is noticeably more shiny and his skin is less flaky and dry. It is a lil pricey but that’s subjective. Smells great. So far so good. I will update after further use
M**S
Douxo S3 Calm Shampoo
It's been a great help whilst shampooing our dog, keeping her clean & stopping her scratching
J**S
great
Works well
R**Y
Douxo S3 Calm shampoo
Product is good. Third time purchase. My dog skin getting better. Will carry on to purchase once current one finish
E**G
Use regularly for better results.
At first few use, it doesn’t seem to do much. But after repeated use for 3 months, can sense the dog skin slightly improving. It is not as effective as Malaseb (another brand), but it is less drying than that.
J**S
happy dog
great my rocky is a new dog after using this
M**A
ChatGPT me lo recomendó xd
cambie de detergente y le provocó alergia a mi perrita maltipoo probé de todo por dos meses aprox y nada servia, era tan grave que tuve que dejarle el collar isabelino día y noche para que no se lastimara, hasta que ChatGPT me dijo que comprara este shampoo en específico y lo usara dos veces por semana al inicio, lo use la primera vez y le perdí fe porque el primer día después del baño se siguió rascando igual, el segundo día casi nada se rasco y para el tercero nada, aun así le deje el collar hasta el segundo baño, pero ahora esta tan tranquila, de verdad funciona, es pequeña pero no necesitas mucho para hacer espuma definitivamente lo seguiré comprando
Trustpilot
1 week ago
3 weeks ago